The 38-year-old, who has won 22 medals, including 11 golds, has been named on the cycling team for the Rio Games, which run from 7 to 18 September.
Storey will be aiming to retain the four titles she won at London 2012.
“It’s just as exciting to be named in the team today as it was for my first Games in Barcelona in 1992,” she said.
“London 2012 was incredible; to win four gold medals at a home Games was a once in a lifetime experience but I can’t wait to get to Rio and hopefully enjoy some more success alongside my Paralympics GB team-mates.”
Storey competed in four Paralympics as a swimmer – in 1992, 1996, 2000 and 2004 – before switching to cycling in 2005.
|Storey’s Paralympic medal tally|
|Barcelona 1992 (swimming)||2 gold, 3 silver, 1 bronze|
|Atlanta 1996 (swimming)||3 gold, 1 silver, 1 bronze|
|Sydney 2000 (swimming||2 silver|
|Athens 2004 (swimming)||2 silver, 1 bronze|
|Beijing 2008 (cycling)||2 gold|
|London 2012 (cycling)||4 gold|
GB squad: Jon-Allan Butterworth, Steve Bate & Adam Duggleby, Jody Cundy, Karen Darke, Hannah Dines, Megan Giglia, Neil Fachie & Pete Mitchell, Lora Turnham & Corrine Hall, Sophie Thornhill & Helen Scott, David Stone, Dame Sarah Storey.
Read more at: http://www.bbc.co.uk/sport/disability-sport/36543522